A drug aims to inhibit EGFR (Epidermal Growth Factor Receptor) in lung cancer cells. If this drug's delivery is inconsistent, which consequence follows regarding the cancer cell cycle?

💡 Explanation

Inconsistent EGFR inhibition leads to unsynchronized cell cycle progression. Because the mitotic checkpoint is weakened, cells can escape mitosis despite DNA errors (mitotic slippage). Therefore, aneuploidy, characterized by abnormal chromosome numbers, becomes likely, rather than controlled arrest, accelerated activation, or changes in metabolism.

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