A patient with a genetic mutation produces abnormal fibrinogen. If this patient experiences a cut, which consequence follows?

💡 Explanation

An abnormal fibrinogen impacts the fibrin polymerization mechanism. Because fibrin stabilization is impaired, the clot is weaker and more prone to breakdown; therefore impaired clot stabilization occurs, rather than accelerated platelet plug formation, which is an earlier step, or enhanced plasminogen activation, which dissolves clots.

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