A patient with liver cirrhosis develops impaired synthesis of clotting factors. Which risk increases as a direct result of insufficient thrombin activation in the coagulation cascade?

💡 Explanation

Insufficient thrombin activation hinders the conversion of fibrinogen to fibrin, a crucial step in clot formation, because thrombin acts as the enzyme that cleaves fibrinogen. Therefore, compromised fibrin formation and clot stabilization occurs, rather than enhanced clot breakdown or platelet function alteration.

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