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← Human Body & HealthA patient with thrombocytosis undergoes routine blood analysis. Which effect results when an elevated platelet count interacts with vWF during hemostasis?
A)Decreased thromboxane A2 production occurs
B)Increased platelet aggregation is initiated✓
C)Fibrinolysis becomes prematurely activated
D)Endothelial nitric oxide synthase is inhibited
💡 Explanation
Increased platelet count combined with von Willebrand Factor (vWF) promotes enhanced platelet adhesion and aggregation because vWF acts as a bridge between platelets and exposed collagen at the injury site, triggering platelet activation. Therefore, more platelets lead to more aggregation, rather than decreased thromboxane production or premature fibrinolysis.
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