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← Human Body & HealthA population of *Pseudomonas aeruginosa* expresses an efflux pump conferring resistance to a beta-lactam antibiotic. Which event most likely allows the bacteria to thrive, despite increasing antibiotic concentration?
A)Increased capsule polysaccharide production
B)Downregulation of porin expression
C)Increased production of siderophores
D)Mutation enhancing efflux pump activity✓
💡 Explanation
A mutation enhancing efflux pump activity allows the bacteria to thrive because it directly increases the rate at which the antibiotic is expelled, therefore decreasing its intracellular concentration. This provides a selective advantage under antibiotic pressure, rather than other defensive mechanisms.
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