An antibiotic-sensitive bacterial population colonizing a catheter experiences increasing concentrations of antibiotic. Which outcome regarding resistance is most likely?

💡 Explanation

Increased antibiotic concentration triggers adaptive responses. Increased efflux pump expression clears the antibiotic from the bacterial cell, decreasing its effectiveness, because this reduces intracellular antibiotic concentrations, therefore promoting survival, rather than immediate cell wall compromise, peptidoglycan synthesis, or altering species competition based on initial antibiotic resistance.

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