An individual with iodine deficiency consumes excess cruciferous vegetables (e.g., broccoli, cabbage). Which consequence follows from the increased intake of glucosinolates?

💡 Explanation

Glucosinolates in cruciferous vegetables inhibit iodine uptake in the thyroid, further impairing thyroid hormone synthesis in iodine-deficient individuals and causing goiter development via hypertrophy and hyperplasia. This is because the thyroid stimulating hormone (TSH) continues stimulating the thyroid gland, therefore promoting growth rather than normal hormone production. The result is goiter.

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