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← Human Body & HealthDuring chronic pain management, which process explains why stimulating A-beta fibers can reduce pain sensation in a patient with peripheral neuropathy?
A)Increased substance P receptor activation
B)Enhanced nociceptor sensitization threshold
C)Gate control theory mediated inhibition✓
D)Upregulation of C-fiber firing rate
💡 Explanation
The gate control theory proposes that A-beta fiber stimulation activates inhibitory interneurons in the spinal cord, reducing pain signal transmission to the brain, because this inhibits the projection neurons. Therefore, stimulating A-beta fibers diminishes perceived pain, rather than exacerbating it through substance P or increased C-fiber activity.
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