During long-term potentiation within hippocampal neurons during sleep, which consequence follows increased synaptic glutamate release?

💡 Explanation

Long-term potentiation (LTP) requires sufficient postsynaptic depolarization to relieve the Mg2+ block on NMDA receptors; because glutamate is the primary excitatory neurotransmitter, increased release enhances depolarization, therefore promoting LTP, rather than reducing AMPA receptor activity or inhibiting retrograde signaling.

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