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Human Body & Health

Following a mRNA vaccine booster, which mechanism explains the enhanced antibody response compared to the primary series, demonstrating long-term immunological memory?

A)Innate immune cell exhaustion occurs
B)Memory B cells undergo affinity maturation
C)Original antigenic sin limits response
D)Passive antibody transfer predominates

💡 Explanation

Memory B cells rapidly differentiate into plasma cells upon re-exposure to the antigen, undergoing affinity maturation to produce higher-affinity antibodies. This heightened response occurs because immunological memory enables a faster and more robust antibody production, therefore B is correct, rather than other options which involve different immunological phenomena or mechanisms.

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