Following a snake envenomation where venom-induced consumption of complement proteins occurs, why does disseminated intravascular coagulation (DIC) risk increase?

💡 Explanation

DIC risk increases due to reduced clearance of apoptotic bodies because complement depletion impairs phagocytosis by macrophages, therefore uncleared apoptotic bodies activate coagulation pathways rather than being cleared by the immune system. Antithrombin activity would decrease in DIC.

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