If a burn patient receives a skin graft lacking fibroblasts, which consequence follows regarding collagen?

💡 Explanation

The primary cells responsible for collagen production in the skin are fibroblasts; therefore, without fibroblasts in the graft, collagen synthesis will be significantly impaired, leading to poor wound healing because collagen provides the structural framework. Rather than increased cross-linking or breakdown, the main problem is the lack of new collagen formation.

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