If a cancer cell line with a mutated epidermal growth factor receptor (EGFR) loses its G1/S checkpoint control, which consequence affecting cell division is most likely?

💡 Explanation

When the G1/S checkpoint is lost, cells with DNA damage progress to S phase, and DNA replication errors accumulate because error checking is bypassed; therefore, genomic instability increases during cell division, rather than apoptosis increasing, which would halt the cell cycle.

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