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Human Body & Health

If a demyelinating disease impairs oligodendrocytes in the central nervous system, which consequence follows for signal transmission?

A)Increased action potential amplitude
B)Slower action potential propagation
C)Enhanced neurotransmitter reuptake
D)Greater postsynaptic receptor sensitivity

💡 Explanation

Demyelination reduces the effectiveness of saltatory conduction, slowing the transmission of action potentials, because myelin sheaths insulate axons, enabling rapid propagation. Therefore, signal transmission slows down, rather than increasing in amplitude or affecting neurotransmitter activity.

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