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Life Sciences & Medicine

If a dermal fibroblast culture is treated with platelet-derived growth factor (PDGF), which consequence follows?

A)Apoptosis signaling will be induced
B)Extracellular matrix degradation accelerates
C)Fibroblast proliferation rate increases
D)Collagen synthesis rate decreases sharply

💡 Explanation

PDGF is a key signal for stimulating cell division and tissue repair. Because PDGF activates receptor tyrosine kinases, triggering intracellular signaling pathways that promote cell cycle progression, therefore fibroblast proliferation increases rather than decreases or triggering apoptosis.

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