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Human Body & Health

If a genetic defect disrupts the kynurenine pathway, an essential metabolic process converting tryptophan into NAD+, which consequence follows?

A)Increased calcium absorption from food
B)Enhanced red blood cell oxygen transport
C)Decreased neural action potential velocity
D)Reduced cellular ATP production capacity

💡 Explanation

The kynurenine pathway is critical for NAD+ synthesis, a key cofactor in cellular respiration. Reduced NAD+ diminishes ATP production because the electron transport chain is impaired, therefore, energy production declines, rather than affecting calcium absorption or nerve conduction speed.

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