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← Human Body & HealthIf a genetically predisposed individual is repeatedly exposed to an allergen such as bee venom, which consequence is most likely due to mast cell degranulation?
A)Increased phagocytosis of allergen
B)Systemic vasodilation and hypotension✓
C)Enhanced T-helper cell activation
D)Reduced eosinophil chemotaxis locally
💡 Explanation
Systemic vasodilation and hypotension become likely because mast cell degranulation releases histamine and other vasoactive mediators, causing blood vessel dilation and decreased blood pressure. Therefore, anaphylactic shock can occur, rather than localized phagocytosis or altered T-cell/eosinophil behavior.
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