If a growth factor receptor mutation constitutively activates cell division signaling in intestinal crypt stem cells, which consequence is most likely?

💡 Explanation

When growth factor receptors are constitutively active, it leads to continuous cell division signaling, overwhelming normal apoptotic pathways; because the checkpoints are bypassed, uncontrolled proliferation occurs. Therefore, the balance tips toward cell survival rather than programmed cell death, rather than quiescence or differentiation.

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