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← Human Body & HealthIf a growth factor receptor mutation in cancer cells disables the intrinsic apoptosis pathway while nutrient supply decreases, which consequence follows?
A)Increased aerobic glycolysis occurs
B)Accelerated necrosis cascade initiated
C)Enhanced mitotic checkpoint activation
D)Reduced caspase activation thresholds✓
💡 Explanation
Decreased nutrient supply increases cellular stress. Because disabled intrinsic apoptosis requires an alternative cell death trigger, reduced caspase activation thresholds emerge because extrinsic signals become more critical for initiating programmed cell death. Therefore, option D is correct, rather than other options relying on functional intrinsic apoptosis.
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