If a weightlifter experiences muscle fatigue during a set, and lactate levels significantly increase in their biceps, which consequence is most likely?

💡 Explanation

Muscle fatigue is linked to increased lactate production, which lowers pH, interfering with calcium handling by the sarcoplasmic reticulum. This impairs muscle contraction because reduced calcium reuptake rates mean less calcium available for cross-bridge cycling. Therefore, calcium reuptake decreases, rather than ATP regeneration increasing or glycogen storage improving, under fatigue-inducing lactate accumulation.

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