If an individual with a genetic predisposition to peanut allergies experiences initial exposure, which consequence relating to immune sensitization follows?

💡 Explanation

Sensitization to an allergen, like peanuts, involves B cells producing IgE antibodies specific to peanut proteins; because these IgE antibodies then bind to mast cells and basophils. Therefore, upon subsequent exposure, crosslinking of these IgE antibodies triggers mast cell degranulation, rather than immediate anaphylaxis, suppression of T-helper cells, or complement-mediated cytotoxicity during initial sensitization.

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