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Human Body & Health

If antibiotic treatment shifts from targeting planktonic bacteria to a biofilm, which consequence follows?

A)Reduced horizontal gene transfer events
B)Decreased mutation rate in bacteria
C)Increased bacterial metabolic activity
D)Upregulation of bacterial efflux pump expression

💡 Explanation

Biofilm formation upregulates efflux pump expression because bacteria within biofilms experience increased stress from antibiotics, therefore, the efflux pump mechanism helps to pump the antibiotic out of the cell, rather than allowing it to accumulate and cause cell death.

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