If cancer cells with mutated growth factor receptors bypass the G1/S checkpoint due to constitutive signaling, which consequence most likely follows regarding apoptosis resistance?

💡 Explanation

Bypassing the G1/S checkpoint, triggered by constitutive receptor signaling, often leads to increased expression of anti-apoptotic proteins, because it promotes cell survival. Therefore, the extrinsic apoptotic pathway activation is suppressed, rather than enhanced, due to the overexpression of survival signals.

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