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Human Body & Health

If cyclical compressive force on a tibia significantly decreases due to prolonged bed rest, which consequence follows regarding bone remodeling?

A)Osteoblast activity increases sharply
B)Osteoclast activity exceeds osteoblast
C)Bone mineral density will acutely increase
D)Mechanical stress inhibits osteocytes

💡 Explanation

Prolonged reduced compressive force leads to increased bone resorption because the mechanotransduction process favors osteoclast activity over osteoblast activity in the absence of normal loading. Therefore, bone density decreases, rather than increases, due to the imbalance favoring resorption.

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