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Human Body & Health

If epinephrine is administered intramuscularly during anaphylaxis, which consequence follows from its interaction with alpha-1 adrenergic receptors?

A)Increased mast cell degranulation
B)Peripheral vasoconstriction increases
C)Bronchial smooth muscle relaxation decreases
D)Systemic IgE production accelerates

💡 Explanation

Epinephrine binds to alpha-1 adrenergic receptors on blood vessels, triggering vasoconstriction because this reduces mucosal edema and increases blood pressure, counteracting the vasodilation of anaphylaxis. Therefore, vasoconstriction increases, rather than vasodilation continuing, and IgE and mast cells are not directly impacted.

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