If extensive scarring inhibits the production of new keratinocytes during wound healing, which consequence follows for collagen synthesis within the dermis?

💡 Explanation

Because keratinocytes release factors stimulating collagen maturation via cross-linking, impaired keratinocyte production reduces the availability of these factors. Therefore, impaired collagen cross-linking is the most likely outcome, rather than increased elastin synthesis or simply fibroblast proliferation.

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