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Human Body & Health

If iodine intake sharply decreases within a population, which consequence follows regarding thyroid hormone regulation?

A)Increased TSH receptor downregulation
B)Elevated TSH secretion and goiter
C)Decreased thyroid peroxidase activity
D)Reduced thyroglobulin synthesis initially

💡 Explanation

Iodine deficiency impairs thyroid hormone synthesis because it is a crucial component of T3 and T4. This leads to decreased negative feedback on the pituitary, therefore TSH secretion increases, stimulating the thyroid gland and causing goiter, rather than the gland remaining quiescent.

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