In a female patient with irregular menstrual cycles undergoing fertility treatment, what causes the multiple ovulations often stimulated by exogenous gonadotropins?

💡 Explanation

Supraphysiological levels of gonadotropins from fertility treatments lead to excessive stimulation of FSH and LH receptors on ovarian cells, which then induce multiple follicles to mature and ovulate, because the normal regulatory mechanisms are overwhelmed. Therefore, multiple ovulations occur, rather than a single ovulation due to typical hormonal feedback.

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