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Human Body & Health

In an asthmatic patient experiencing bronchospasm after allergen exposure, which mechanism explains why beta-2 agonist inhalers provide rapid relief?

A)Blocking histamine receptor activation
B)Stimulating smooth muscle relaxation
C)Inhibiting mast cell degranulation
D)Reducing leukotriene production locally

💡 Explanation

Beta-2 agonists cause bronchodilation by stimulating beta-2 adrenergic receptors on bronchial smooth muscle cells, leading to relaxation of the constricted airways because cAMP levels increase; therefore, airway resistance decreases rapidly, rather than affecting histamine release or leukotriene production directly.

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