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Human Body & Health

In chronic kidney disease, which consequence follows from reduced erythropoietin (EPO) production due to peritubular fibroblast deficiency?

A)Increased bone marrow activity
B)Elevated reticulocyte production
C)Normocytic normochromic anemia develops
D)Increased iron absorption in duodenum

💡 Explanation

Reduced EPO hinders erythropoiesis, the mechanism driving red blood cell production in the bone marrow. Because the red blood cells formed are normal in size and hemoglobin content but insufficient in number, normocytic normochromic anemia results. Therefore, the correct answer is C, rather than increased erythropoiesis or iron absorption.

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