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Human Body & Health

What causes impaired motor skill consolidation after sleep deprivation?

A)Decreased cortisol receptor expression
B)Reduced slow-wave sleep spindle activity
C)Elevated systemic inflammatory cytokine levels
D)Increased sympathetic nervous system tone

💡 Explanation

Reduced slow-wave sleep diminishes thalamocortical spindle activity, which is essential for transferring motor skill memories from the hippocampus to the motor cortex. Because slow-wave sleep is disrupted, therefore memory consolidation is impaired, rather than other hormonal or inflammatory processes being the primary driver.

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