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Human Body & Health

What distinguishes glycogen synthesis from gluconeogenesis in the liver during periods of hyperglycemia?

A)Both pathways occur at equal rates
B)Glycogenolysis becomes the dominant pathway
C)Glycogen synthesis consumes ATP, gluconeogenesis produces it
D)Gluconeogenesis uses glycogen as primary substrate

💡 Explanation

Glycogen synthesis uses ATP to convert glucose into glycogen for storage, while gluconeogenesis generates glucose from non-carbohydrate sources and produces ATP; because the liver aims to store excess glucose rather than create more, therefore glycogen synthesis is favored, rather than gluconeogenesis, during hyperglycemia.

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