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When estimating protein sequence combinations from amino acid alphabets, which effect increases if identical amino acids are not distinguished?

A)Undercounting of total possibilities
B)Overcounting of distinct sequences
C)Accurate representation of combinations
D)Equal distribution of sequences

💡 Explanation

The sequence space gets severely overcounted because the identical amino acids are treated as unique, when in reality permuting them creates the same protein. The inclusion-exclusion principle requires correcting this overcounting, therefore B is correct, rather than the other options which assume accurate or undercounted possibilities.

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