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← Logic & PuzzlesWhen estimating protein sequence combinations from amino acid alphabets, which effect increases if identical amino acids are not distinguished?
A)Undercounting of total possibilities
B)Overcounting of distinct sequences✓
C)Accurate representation of combinations
D)Equal distribution of sequences
💡 Explanation
The sequence space gets severely overcounted because the identical amino acids are treated as unique, when in reality permuting them creates the same protein. The inclusion-exclusion principle requires correcting this overcounting, therefore B is correct, rather than the other options which assume accurate or undercounted possibilities.
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