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← ScienceWhich characteristic dictates the catalytic efficiency of enzymes?
A)Formation affinity for unstable transition states✓
B)Highest binding energy to ground state
C)Rate of degradation product removal
D)Enzyme molecular weight influences stability
💡 Explanation
The enzyme's affinity to the transition state dictates turnover, because transition state stabilization reduces the required Gibbs free energy via orbital steering. Therefore, highest catalytic efficiency is achieved, rather than merely binding reactant to lower activation.
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