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← ScienceWhich condition enhances mRNA stability using AU-rich elements?
A)Deadenylation via accelerated mRNA decay
B)ARE-BP binding inhibits mRNA turnover✓
C)Exosome degradation after primary cleavage
D)Upstream ORF translation increases destabilization
💡 Explanation
ARE-BP binding inhibits mRNA turnover because AU-rich elements interacting with ARE-binding proteins block mRNA degradation pathways using the mechanism of steric hindrance; therefore stability increases, rather than decreasing it as exosome activity would.
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