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← ScienceWhich consequence results when a catalyst impurity impacts enzyme kinetics?
A)Increased activation energy requirement reduces catalysis✓
B)Lowered system equilibrium inhibits substrate products
C)Enzyme active site conformation changes minimally
D)Initial reaction rate will significantly increase
💡 Explanation
Contaminant binding increases the enzyme's energy barrier via Induced fit distortion, inhibiting the catalysis mechanism, because substrate access is impaired. Therefore, higher activation energy is needed, rather than substrate modification increasing reaction speed.
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