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Which consequence results when disulfide bridges are disrupted biochemically?

A)Protein misfolding and loss of function
B)Increased hydrophobic interactions with water
C)Enhanced stability at higher temperatures
D)Increased enzymatic hydrolysis of peptide bonds

💡 Explanation

Misfolding leads to a loss of function because disruption prevents the covalent cross-linking from stabilizing its folded state via disulfide rearrangement, therefore affecting protein folding. The protein unfoldeds rather than having its activity affected by temperature.

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