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← ScienceWhich consequence results when enzyme conformational change is inhibited?
A)Substrate binding affinity decreases overall✓
B)Reverse reaction rate increase measured
C)Equilibrium concentrations shift dramatically
D)Product inhibition becomes wholly ineffective
💡 Explanation
Enzyme conformational change is essential for induced fit, and reduced flexibility hinders the lock-and-key *mechanism* and effective binding; therefore substrate affinity decreases, rather than options B/C pertaining equilibrium. Option D also involves related allosteric effects.
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