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Human Body & Health

Which consequence results when hypothalamic-pituitary axis negative repression fails?

A)Hormone level remains inappropriately elevated
B)Metabolic downregulation induces hypothyroidism acutely
C)Glucose uptake becomes extremely hypersensitive
D)Sodium channel activity prevents cellular firing

💡 Explanation

Failure of negative feedback causes continuous hormone production via broken repression, because no signal inhibits secretion, therefore creating sustained elevated levels of the hormone, rather than suppressed hormone levels or changes elsewhere.

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