Which consequence results when intramolecular hydrogen bonding dominates enzyme active sites?

💡 Explanation

Reduced substrate affinity occurs because pre-existing intramolecular hydrogen bonds within enzyme active sites hinders substrate binding rather than promoting it. Therefore, a substrate has to overcome greater energetic barriers rather than easily fitting, decreasing binding; substrate affinity worsens.

• Which outcome arises when isotopes transition into more stable configurations?
• Which consequence results when a sodium chloride crystal's edge fractures?
• Which outcome occurs at the Curie temperature in iron?
• Which consequence results when the activation energy changes to increase the reverse rate constant?
• Which effect occurs on light's frequency owing to gravitational redshift?
• Which outcome characterizes an intrinsic semiconductor's behavior near absolute zero?