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← ScienceWhich effect occurs when a protein misfolds due to temperature?
A)Disruption of intramolecular hydrogen bonds✓
B)Increased alpha helix formation rates
C)Decreased van der Waals forces overall
D)Enhanced disulfide bridge crosslinking
💡 Explanation
Protein denaturation results from disruption of intramolecular hydrogen bonds, causing unfolding because hydrogen bonds maintain the protein's tertiary structure; therefore loss of these bonds unfolds its native conformation, rather than enhanced folding or specific interactions.
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