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← ScienceWhich factor limits reaction throughput in enzyme bioreactors?
A)Substrate diffusion to enzyme active site✓
B)Accumulation of product inhibits catalysis
C)Denaturation rate depends on concentration
D)Stirring reduces wall shear stress
💡 Explanation
Substrate diffusion to active sites limits throughput because the Michaelis-Menten kinetics depend on encounter rate. Slower diffusion thereby constrains the reaction rate rather than denaturation depending directly on concentration.
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