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← ScienceWhich inaccuracy arises when calculating a protein's structure using density functional theory?
A)Electron correlation is poorly approximated✓
B)Relativistic effects become significant
C)Vibrational entropy contributes significantly
D)Solvent interactions are overemphasized
💡 Explanation
Calculations can misrepresent true structure because electron correlation is approximated by the exchange-correlation functional in density functional theory, therefore inaccurate models often occur rather than the alternatives that require molecular dynamics.
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