Which mechanism explains shivering thermogenesis in cold-stressed newborn mammals?

💡 Explanation

When newborn mammals experience cold stress, uncoupled mitochondrial oxidative phosphorylation in brown fat generates heat by dissipating the proton gradient, leading to shivering thermogenesis as muscle activity is still limited. Therefore, uncoupled oxidation results, rather than vasodilation, insulin sensitivity, or sweating, which involve alternate mechanisms in other thermoregulatory responses.

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