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Life Sciences & Medicine

Which mechanism explains why a developing limb bud differentiates into specific structures?

A)Increased protein synthesis rates globally
B)Reduced epigenetic DNA methylation markers
C)Localized morphogen concentration gradients
D)Ubiquitous expression transcription factor activity

💡 Explanation

Localized morphogen concentration gradients determine cell fate through differential gene expression. Because cells respond differently based on their exposure to these morphogens, tissues form distinct patterns; therefore localized gradients, rather than uniform changes, drive specific differentiation.

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