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Nature & Animals

Which mechanism increases metabolic heat during prolonged shivering in mammals?

A)Uncoupling protein 1 activation in mitochondria
B)Vasodilation of dermal blood vessels
C)Reduced thyroid stimulating hormone secretion
D)Increased glycogenolysis in liver cells

💡 Explanation

During prolonged shivering, activation of uncoupling protein 1 (UCP1) in mitochondria occurs because proton gradients dissipate, leading to heat generation instead of ATP production, massively increasing metabolic rate. Therefore brown fat UCP1 activation specifically causes thermogenesis, rather than vasodilation, reduced TSH, or liver glycogenolysis, which operate through separate pathways.

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