Which mechanism limits the effectiveness of certain polymers as drug-delivery vehicles at high molar mass?

💡 Explanation

When polymer molar mass increases, the drug's slower movement through tissues occurs because the diffusion coefficient decreases with increasing molecule size due to frictional drag, compromising penetration. Therefore, slower diffusion limits effectiveness, rather than faster entanglement reduction, degradation changes, or preciipitation, which require altered molecular interactions.

• Which consequence results when a palladium membrane hydrogen purifier develops pinhole leaks?
• Which optical consequence occurs when unpolarized light encounters dichroic material?
• Which outcome increases within a Carnot heat engine utilizing R-134a when the condenser pressure rises unexpectedly?
• Which outcome results when high voltage causes dielectric breakdown in solid barium chloride?
• Which risk increases when using misaligned polarizing filters?
• Which risk increases when gallium arsenide crystals experience strain?