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← ScienceWhich outcome is accelerated by reduced disulfide bridging?
A)Protein unfolding and degradation rate✓
B)Enhanced proteolytic cleavage resistance
C)Increased protein thermal stability
D)Reduced aggregation in amyloid fibrils
💡 Explanation
Protein unfolding accelerates because weakening of tertiary structure relies on covalent disulfide bridging; this leads to accelerated degradation rather than protection. Therefore, unfolding increases rather than stability because disulfide bonds maintain stability.
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