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Human Body & Health

Which outcome occurs when antithrombin III's activity is significantly reduced in blood plasma?

A)Increased fibrinolysis dissolves clots
B)Platelet aggregation is directly inhibited
C)Vitamin K dependent clotting reduced
D)Uncontrolled activation of the clotting cascade

💡 Explanation

Reduced antithrombin III results in uncontrolled clotting cascade activation because this protein normally inhibits thrombin and other coagulation factors. Therefore, unchecked coagulation occurs, rather than fibrinolysis or direct platelet inhibition which operate via different pathways.

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