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← ScienceWhich outcome occurs when continuously increasing an inhibitor concentration in a non-competitive enzymatic reaction?
A)Reaction rate progressively approaches zero✓
B)Affinity of enzyme increases greatly
C)Substrate saturation occurs prematurely
D)Initial velocity plateaus and stabilizes
💡 Explanation
Increasing inhibitor concentration progressively disables enzymes. The reaction rate asymptotically approaches zero because non-competitive inhibitors reduce enzyme activity via allosteric modulation, rather than directly blocking the active site; therefore, the reaction halts rather than achieving a different equilibrium.
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